Trichocereus pachanoi - San Pedro Cactus
The San Pedro Cactus, or Trichocereus pachanoi, was in use at the very beginning of Andean civilization when it was highly prized as the “materia prima” (raw material) of the shamans of that era. In the central Andes district of Peru, as well as in the surrounding desert regions, the cactus has been an important ritual plant for thousands of years.

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  • Why Entheology.org?
    Our simple and concise mission statement including information regarding submissions. We pay you for reprint rights on any research paper we'd like to include here at Edoto...just click for details.

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  • Plants of the Gods
    Absolute essential read for anyone interested in sacred entheogens. Includes detailed history and preparation of 97 psychoactive and/or sacred plants.

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  • Annual Causes of Death in America
    The REAL truth is the most sobering statistic.

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  • Annual Causes of Death in America
    The REAL truth is the most sobering statistic.

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  • Extracting Salvinorin from Salvia Divinorum
    This is a concise extraction method for educational purposes only.

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  • Monoamine Oxidase Inhibitors
    Extremely important information regarding MAOI's, complete with Diet Card.

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  • Traditional Quid Preparation
    Information regarding the traditional praparation of Salvia divinorum for divination by the Mazatecs.

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  • Pharmacology of Bufotenine
    Exhaustive case study regarding Bufotenine, 5-MEO-DMT, and related substances.

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  • Study on Calea Zacatechichi (Dream Herb)
    Calea zacatechichi is a plant of extensive popular medicinal use in Mexico. An infusion of the plant is has been reported to have psychotropic properties that have been clinically-proven to induce dreaming, and increase the frequency of dreams as well.

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  • In Depth Report Regarding DMT
    In this article I wish to draw attention to a strange property of DMT which sets it apart from other psychedelics, namely, it's ability to place users in touch with a realm that is apparently inhabited by discarnate entities of an intelligent nature.

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  • The Science of Ethnobotany
    Ethnobotanists share two decades of experience living with the indigenous peoples of Central and South America, the Caribbean, and Southeast Asia.

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  • Entheogens and the Future of Religion
    The book should prove to be a welcome complement to other serious studies in mysticism (including those that take a fundamentally different tack).

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  • Tukanoans
    The Tukanoans are one of the most known cultures that utilize ayahuasca as their sacrament. They are one of about 70 tribes who share this practice.

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  • Ayahuasca, shamanism, and curanderismo in the Andes
    The term ayahuasca comes from the Quechua, meaning literally "the vine of souls," although it is also called "the visionary vine" or the "vine of death." The folk term refers to the botanical species of liana known as Banisteriopsis Caapi , which is also

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  • The Santo Daime Religion
    In this paper, the reader will be introduced to the sect of Santo Daime, a Brazilian religion which combines Christianity with the indigenous practice of using ayahuasca, a native entheogenic plant.

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  • Santo Daime Church Wins Court Case
    Freedom of Religion versus the Psychotropic Substance Treaty - The Verdict

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  • Ayahuasca: Human Consciousness and the Spirits of Nature
    Anything with the name Ralph Metzner even remotely attached to it is a safe buy. An elder statesman responsible for dramatic shifts in consciousness within this nation and throughout the world...

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  • DMT: The Spirit Moecule
    Covering a groundbreaking psychedelic substance that is actually found in human cerebrospinal fluid, Rick Strassman tells a first-person story of his research on the profoundly mysterious substance dimethltryptamine (DMT).

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  • The World As You Dream It: Shamanic Teachings from the Amazon and Andes
    John has done a lot to honor and preserve the indigenous teachings and the ethnobotanical environment.

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  • Shapeshifting: Shamanic Techniques for Global and Personal Transformation
    John has done a lot to honor and preserve the indigenous teachings and the ethnobotanical environment.

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  • Canada to Decriminalize Cannabis
    The Liberal government is preparing to move ahead in the new year with legislation to decriminalize marijuana, Justice Minister Martin Cauchon said yesterday.

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  • Solubility of Active Components – Quick Guide
    Brief discussion on active components of plants and whether they were traditionally extracted into alcohol, water, or other solvents.

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  • Argyreia nervosa - Hawaiian Baby Woodrose
    Hawaiian Baby Woodrose seeds are perhaps one of the least understood of modern-day entheogens and exotic botanicals. There is much controversy in regards to its true place in Shamanic and traditional history outside of its native culture and home; India.

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  • Argyreia nervosa - Hawaiian Baby Woodrose
    Hawaiian Baby Woodrose seeds are perhaps one of the least understood of modern-day entheogens and exotic botanicals. There is much controversy in regards to its true place in Shamanic and traditional history outside of its native culture and home; India.

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  • Leonotis leonurus - Lion's Tail
    Smoked by the Hottentot tribes smoke the resinous flowering tops and leaves from this plant as a euphoriant.

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  • Leonurus sibiricus - Siberian Motherwort
    Leaves from Siberian Motherwort (Marihuanilla) are collected while the plant is in bloom, dried, and then smoked in either a pipe or with rolling papers. No toxic dosage is known and typically 1 to 2 grams of the dried leaf is enough for one rolled cigare

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  • Botany of Peyote (Lophophora williamsii)
    The peyote cactus is a flowering plant of the family Cactaceae, which is a group of fleshy, spiny plants found primarily in the dry regions of the New World.

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  • Lycoperdon mixtecorum - Bovista
    PUFFBALLS (Lycoperdon mixtecorum and L. marginotum) are used by the Mixtec Indicins Of Oaxaca, Mexico as auditory hallucinogens.

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  • Mandragora officinarum - Mandrake
    Mandrake is unquestionably the most famous magical plant, and the most widely used psychoactive of ancient through medieval times. Mandrake use is much less common today, but certain parts of the world still value its medicinal and magical properties.

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  • Maquira sclerophylia - Rapa dos Indios
    In the Pariana region of the central Amazon in Brazil, the indians formerly prepared a hallucinogenic snuff of the dried fruits. The snuff was taken in tribal ceremonials, but encroachment of civilization has obliterated it's use.

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  • Mimosa hostilis - Jurema Tree
    The preparation of the brew from fresh Jurema root bark for trance possession rituals, is, in itself, a complex ritual of the Atikum tribe.

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  • Mitragyna speciosa - Kratom
    Kratom is traditionally only used in Thailand, although some use in Malaysia has been reported. Use dates far enough back that its beginning can't be determined. It is often used as a substitute for opium when opium is unavailable, or to moderate opium ad

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  • Mucuna pruriens - Cowhage
    M. pruriens is a leguminous climbing plant, with long, slender branches, alternate, lanceolate leaves on hairy petioles, 6 to 12 inches long, with large, white flowers, growing in clusters of two or three, with a bluish-purple, butterfly-shaped corolla.

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  • Nymphaea caerulea - Blue Lily / Blue Lotus
    Creating a feeling of well being, euphoria and ecstasy, Nymphaea caerulea (blue lotus) is a water plant growing on the shores of lakes and rivers.

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  • Oncidium ceboletta - Hikuri Orchid
    Oncidium longifolium is known as a peyote replacement among the Tarahumara.

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  • Macropiper Excelsum - Maori Kava
    This subspecies from the New Zealand mainland is the variety used by the Maori in their medicines and rituals and belongs to the kava family.

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  • Panaeolus spinctrinus - Hoop-Petticoat
    Under construction.

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  • Panaeolus subbalteatus - Dark-rimmed Mottlegill
    Panaeolus subbalteatus is a psilocybin-containing mushroom that also has large amounts of serotonin and 5-hydroxytryptophan, which may account for its reportedly relatively mellow effects.

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  • Pandanus
    Natives of New Guinea employ the fruit of an unidentified species of Pandanus for hallucinogenic purposes, unfortunately little is known of this use.

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  • Peganum harmala - Syrian Rue
    The seeds, as well as the roots, of P. harmala contain a mixture of the harmala alkaloids, armine and harmaline. When admnstered to humans, the harmala alkaloids are serotonin antagonists, CNS stimulants, hallucinogens and extemely potent, short term MAO

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  • Pelecyphora aselliformis - Peyotillo
    P. aselliformis is a well known medicinal peyote sold in the markets of San Luís Potosí, Mexico, and is used as a remedy for fevers and rheumatic pains. Extracts have also been shown to have antibiotic activity.

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  • Pernettya furens - Hierba loca
    The fruit of tagili, of Ecuador, is well recognized as poisonous, capable of inducing hallucinations and other psychic alterations as well as affecting the motor nerves.

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  • Petunia violaceae - Shanin
    SHANIN (Petunia violacea) is one of the most recently reported hallucinogens. It is taken by the Indians in Ecuador to induce the sensation of flight.

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  • Petunia violaceae - Shanin
    SHANIN (Petunia violacea) is one of the most recently reported hallucinogens. It is taken by the Indians in Ecuador to induce the sensation of flight.

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  • Phalaris arundinacea - Red Canary Grass
    The plant contains DMT, beta-carbolines, 5-MEO-demethyltryptamine, and trace amounts of bufotenine.

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  • Phragmites australis - Common Reed
    A perenniel grass with a long association with humans, the common reed is native to Eurasia and Africa but has spread all over the world with people, even though it has practically never been cultivated.

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  • Psilocybe cubensis - San Isidro
    Psilocybe cubensis is distinguished by its slightly curved caps which can grow up to 8 cm in diameter, and feature a yellow or golden center. Like all mushrooms containing psilocybin, Psilocybe cubensis provides a potent visionary experience, often with s

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  • Psilocybe cyanescens - Wavy Cap
    Psilocybe cyanescens is a psilocybin/psilocin-containing mushroom most commonly found in the Pacific Northwest, but the most potent varieties grown in and are used by mushroom cults in central Europe.

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  • Psilocybe mexicana - Teonanacatl
    Few plants of the gods have ever been held in greater reverence than the sacred mushrooms of Mexico. So hallowed were these fungi that the Aztecs called them Teonancatl ("divine flesh") and used them only in the most holy of their ceremonies. Even though,

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  • Psilocybe semilanceata - Liberty Cap
    Psilocybe Semilanceata was first described in 1900, by Civil War veteran, Charles McIlvaine in his seminal mycological treatise “One Thousand American Fungi,” where he described the Liberty Cap and all of its “strange effects.” However, it wasn’t until 19

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  • Psychotria viridis - Chacruna
    The classical principle admixtures of Ayahuasca and Yagè commonly employed throughout Amazonian Peru, Ecuador and Brazil. Related to the coffee plant in a large genus of over 700 species, Psychotria viridis is a small glabrous tree or shrub reaching 14 fo

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  • Rynchosia phaseoloides - Piule
    The beautiful red and black beans of several species of Rhynchosia may have been eployed in ancient Mexico as an hallucinogenic.

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  • Salvia divinorum - Diviner's Sage
    Salvia divinorum is a perennial labiate used for curing and divination by the Mazatec Indians of Oaxaca, Mexico. The psychotropic effects the plant produces are compared to those of the other hallucinogens employed by the Mazatecs, the morning glory, Rive

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  • Sceletium tortuosum - Kanna
    The family Mesembryanthemaceae contains many pharmacologically active species. One of the most utilized by native peoples in South Africa was the genus Sceletium(Kanna), for which whole tribes would travel hundreds of miles to pick a years supply.

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  • Scirpus atrovirens - Bakana
    One of the most powerful herbs of the Tarahumara of Mexico is apparently a species of Scirpus.

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  • Solandra grandiflora - Chalice Vine
    Many aboriginal Indian tribes from central Mexico and northern Central America have long believed in the magical and mysterious powers of Solandra grandiflora, (Kieli/Kieri-Plant of the god’s), some of these tribes include the Huastec, Huichol, and Mixtec

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  • Tabernatnthe Iboga - Iboga
    Iboga is basic to the Bwiti cult and other secret societies in Gabon and the Congo.

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  • Tanaecium nocturnum - Koribo
    This climbing vine grows natively in Central America, especially in southern Panama. It is also native to the Amazon, West Indies and the Yucatan Peninsula, Mexico. Though this plant has not been extensively studied, there is ethnographic research detaili

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  • Teltrapteris methystica - Caapi-pinima
    ANOTHER KIND OF CAAPI is prepared from Tetrapteris methistica, a forest vine also belonging to the family Malpighioceae.

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  • Virola theiodora - Cumala Tree
    Most, if not all, species of Virola have a copious red "resin" in the inner bark. The resin from a number of species is prepared as an hallucinogenic snuff or small pellets.

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  • Vocanga - Vocanga
    Voacanga africana is one of the well guarded secrets of the African Magic Healers. Little is know about the actual use of the seeds and the bark of several Voacanga species (including V.africana), other than that the plant is held in high esteem for ritua

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  • How to Germinate Seeds
    Great article from a great online seed vender; Alchemy Works.

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  • To Save the Forest, the Trees Must Go
    In the name of science, the United States Forest Service has proposed the experimental logging of half a million acres in two forests in the Sierra Nevada...

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  • The Bwiti Religion and Tabernanthe iboga
    The use of vegetable hallucinogens by humans for religious purposes is very ancient, probably even older than its use for healing, magic or teaching purposes. The profound alterations in one's state of consciousness brought about by the use of a hallucino

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  • Mao Inhibitor Recipe Simplified
    This is a powerful MAO inhibitor, and should be treated VERY carefully!

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  • Studies of Salvia divinorum (Lamiaceae),
    Salvia divinorum Epling & Játiva-M. is one of the vision-inducing plants used by the Mazatec Indians of central Mexico. The present status of research is summarized.

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  • Piper methysticum - Kava Kava
    Kava Kava is also known by the names Ava, Ava Pepper, Intoxicating Pepper, Kawa Awa, Kawa Kawa, Wati, Yogona, and Waka. This herb, a member of the pepper family, grows as a bush in the South Pacific.

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  • Piper methysticum - Kava Kava
    Kava Kava is also known by the names Ava, Ava Pepper, Intoxicating Pepper, Kawa Awa, Kawa Kawa, Wati, Yogona, and Waka. This herb, a member of the pepper family, grows as a bush in the South Pacific.

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  • Modern Day Shamanism in Hawaii
    Serge is doing his part to save the shaman traditions of his culture when he formed Aloha International; a world-wide network of people studying and practicing the Hawaiian shamanic traditions.

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  • Use of Psychoactive Snuff in Pre-Columbian Chile
    One notable feature of the Pre-Columbian San Pedro culture is the high incidence of snuffing implements. The most common of the snuffing kits found in San Pedro de Atacama consists of a woolen bag containing a wooden rectangular snuff tray, a snuffing tub

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  • Native Hallucinogen Piptadenias
    From very remote times, the indigenous inabitants of various parts of South America have been aware of the hallucinogenic properties of diverse species of the genus Piptadenia. The purpose of the present study is to bring out the salient facts concerning

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  • Argemone mexicana - Prickly Poppy
    This is an extraodinarily interesting psychoactive plant, which is just now being rediscovered by psychonauts everywhere. Rich in history with the Aztecs, this poppy plant is presently legal worldwide.

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  • Wormwood (Artemisia absinthium)
    Wormwood is an ancient plant who’s roots can be traced back to ancient times. Most don’t think about this one fact, but the Greek goddess; Artemis is where this plant gets its name from. Most scholars believe that this was a name attributed to all Artem

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  • Lactuca virosa - Wild Lettuce, Green Endive, Lettuce Opium
    The Hopi smoked the dried resin, or sap, obtained from the plant. The Hopi believe that induced dream states contain more information about reality than the conscious waking state. Wild lettuce, aka lettuce opium, is said to enhances the vividness of dre

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  • FDA Makes False Claims About Marijuana
    Last Friday, 24 members of Congress demanded that the Food and Drug Administration (FDA) account for its disingenuous April 20 statement claiming that “no sound scientific studies” support the medical use of marijuana.

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  • FDA Makes False Claims About Marijuana
    Last Friday, 24 members of Congress demanded that the Food and Drug Administration (FDA) account for its disingenuous April 20 statement claiming that “no sound scientific studies” support the medical use of marijuana.

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  • FDA Makes False Claims About Marijuana
    Last Friday, 24 members of Congress demanded that the Food and Drug Administration (FDA) account for its disingenuous April 20 statement claiming that “no sound scientific studies” support the medical use of marijuana.

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  • Supreme Court Sides With Church in Ayahuasca Case
    In a UNANIMOUS RULING Tuesday, the Supreme Court decided that O Centro Espirita Beneficiente Uniao do Vegetal (UDV), a religious congregation based in New Mexico, can use ayahuasca, a hallucinogenic tea, in its ceremonies.

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  • Supreme Court Sides With Church in Ayahuasca Case
    In a UNANIMOUS RULING Tuesday, the Supreme Court decided that O Centro Espirita Beneficiente Uniao do Vegetal (UDV), a religious congregation based in New Mexico, can use ayahuasca, a hallucinogenic tea, in its ceremonies.

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  • Papaver somniferum - Opium Poppy
    Ancient peoples considered this a sacred medicinal plant and a source of powerful shamanic potions. The opium poppy was a magical ritual plant among the Germanic tribes. The opium poppy is one of the most significant plants in history, having had consider

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  • Acorus Calamus var. Americanus
    Calamus was originally noted to have hallucinogenic properties through ethnobotanical research dating back to the 1960s. However, sweet flag has been held in high esteem by North American Indians for hundreds of years.

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  • Peyote (Lophophora williamsii)
    Peyote (Lophophora williamsii grows in South-Eastern America and in northern regions of Mexico. In Mexico, peyote has been used for divination in shamanic rituals and in the treatment of ailments for at least 10,000 years.

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  • Tagetes lucida - Marigolds
    Tagetes lucida, widely identified as a powerfully psychoactive strain of the marigold flower, was first documented by the Aztecs. They used Tagetes lucida in their ritual incense they referred to as yyauhtl. This name was derived from the Aztecan word uja

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  • White Lotus - Nymphaea ampla
    The effects of the flower when prepared as a tea or decoction and ingested are said to be much like the opiate apomorphine. White lotus actually contains aporphine, which is closely related to apomorphine, differing only in the lack of two hydroxyl group

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  • Passiflora - Passion Flower
    The psychoactive properties of the Passiflora genus as a whole is still awaiting thorough ethnopharmacological study, however there are several species that have a rich history as entheogens.

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  • Yohimbe - Pausinystalia yohimba
    In addition to its sexual stimulant and aphrodisiac qualities, the bark of the yohimbe tree has been reported to also be hallucinogenic when smoked. The psychoactive effects are primarily due to the main active constituent yohimbine. Yohimbine has sympath

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  • Withania somnifera - Ashwagandha
    Widely used back in Mesopotamia for its medicinal and narcotic properties, this member of the Nightshade Family, was well known in ancient Egypt and characterized and classified as a sakrân intoxicant in Old Arabic.

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  • A Psychedelic ‘Problem Child’ Comes Full Circle
    Upon the death of psychedelic pioneer Dr. Albert Hofmann, Benedict Carey of the Ne York Times examines the history, and the potential therapeutic future, of LSD is examined.

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  • The Future of Psychedelics
    Author Daniel Pinchbeck discusses the 2008 World Psychedelic Forum held recently in Switzerland, and the potential for studying psychedelic therapies in the shifting world political climate.

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  • Self-Experimenters: Psychedelic Chemist Explores the Surreality of Inner Space, One Drug at a Time
    Alexander Shulgin endured a government crackdown and hallucinations of his bones melting in pursuit of new mind-bending compounds.

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  • Research On Psychedelics Moves Into The Mainstream
    In-depth article on the new, emerging studies of the psychotherapeutic uses of psychedelic drugs such as LSD, MDMA and Psilocybin.

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  • Autism, ADD, ADHD and Marijuana Therapy
    Medical Marijuana research over the last six years demonstrates a link to marijuana use and alleviating symptoms of ADD, ADHD, depression, pain and other chronic conditions.

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  • Psst... Government-Supplied Marijuana Program Turns 30
    May 10th marked the 30th anniversary of a little-known federal government program - referred to as a Compassionate Investigational New Drug (IND) program - which supplies medical marijuana to only a handful of patients.

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  • Could an Acid Trip Cure Your OCD?
    Research intensifies into the use of psychedelics in the treatment of psychological conditions such as depression, PTSD, obsessive compulsive disorder and anxiety. Patients undergoing treatment for life-threatening diseases such as cancer are finding answ

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  • Khat Out of the Bag
    A Somali national residing in London was caught with 10 kilogrammes of khat at the Malta International Airport (MIA) last week. This was the second time that the drug was discovered by the authorities in Malta. But it is well known in other parts of the w

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  • The Shroom Tragedy
    Magic mushrooms are on the verge of being outlawed by the Dutch government for the usual sensationalized reasons as everywhere else.

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  • The Shroom Tragedy
    Magic mushrooms are on the verge of being outlawed by the Dutch government for the usual sensationalized reasons as everywhere else.

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  • Blood is Thicker Than Friends
    Fiji's interim Prime Minister Commodore Voreqe Bainimarama describes his experience with a Vanuatu kava session.

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  • Incense May Relieve Depression and Anxiety Naturally
    Researchers find psychoactive link between burning frankincense incense and relieving symptoms of anxiety and depression.

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  • Brazil Appeals Court Rules Drug Possession Not a Crime
    At the end of March, a Brazilian appeals court in São Paulo declared that possession of drugs for personal use is not a criminal offense. Several lower courts had previously ruled in the same way, but the ruling from the São Paulo Justice Court's 6th Crim

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  • Will Harvard Drop Acid Again?
    Dr. John Halpern of Harvard University conducts research through human clinical trials into the medicinal value and applications of LSD and psilocybin. Joining forces with Halpern is Rick Doblin, founder of the Multidisciplinary Association for Psychedeli

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  • Low-Dose Psilocybin Brings Relief To Cluster-Headache Sufferers
    Anecdotal evidence and comprehensive, scientific case studies point to successful treatment of cluster headaches with psilocybin mushrooms.

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  • What Herbs May Help People With Anxiety
    Dr. Michael W. Kahn, Assistant Professor in the Department of Psychiatry at Harvard Medical School, and Director of Ambulatory Psychiatry at the Beth Israel Deaconess Medical Center in Boston, discusses alternative herbal therapies for treating anxiety.

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  • How the Internet Fuels the Global Psychedelic Community
    This year and the next, the United Nations will evaluate the War on Drugs. Since its official start in 1998 we have been bombed with official statistics on drug use, drug addiction, drug trafficking, street prices, courtcases and all the like. But what do

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  • US Leads World in Substance Abuse, WHO Finds
    The United States leads the world in rates of experimenting with marijuana and cocaine despite strict drug laws, World Health Organization researchers said on Tuesday. Countries with looser drug laws have lower rates of abuse, the researchers report in t

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  • Absinthe - Green Fairy - Wormwood
    Now that the ban on absinthe has been lifted in the United States, as well as around the rest of the world, all of us now are able to enjoy The Green Fairy again in all her psychoactive and sometimes psychedelic glory that inspired many great artists.

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  • Turbina corymbosa - Ololiuqui
    Ololiuqui is the Aztec name for the seeds of certain convolvulaceous plants which have been used since prehispanic times by the Aztecs and related tribes, just as the sacred mushrooms and the cactus peyote have been used in their religious ceremonies for

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  • The Land of the Lotus Smokers
    Metaphor and drug use from Homer's the Illiad and he Odyssey, and modern day use of the lotus flower in extracts and herbal blends.

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  • Theobroma cacao
    Cacao truly is a "Food of the Gods", especially now that it's been clinically-proven to be extraordinaily good for our bodies. Yes, chocolate is indeed derived from cacao and has extraordinary nutritional properties, as well as psychoactive and aphrodisi

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  • Might the Gods be Alkaloids?
    The question related in the title of our presentation addresses the role and use of psychoactive plants, throughout the process of human evolution, as inducers of altered states of consciousness.

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  • Marc Emery, Canada's Prince of Pot
    In November 2002, Cannabis Culture publisher Marc Emery completed his second run for Mayor of Vancouver, Canada's West Coast cannabis capital. The renowned pot seed merchant placed fifth on the crowded ballot, participating in all major debates and campai

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  • Who Will Be Obama’s Pick For ‘Drug Czar’?
    by Allen St. Pierre, NORML Executive Director.

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  • Healing and Regenerative Effects of Ayahuasca
    One writer's personal journey into healing and self-awareness at Camp Ayahuasca.

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  • Russia Bans Blue Lotus Smoking Blends
    Light drugs are still available in free sale in Russia despite the official decree issued by Surgeon General Gennady Onischenko. One can purchase a blend of dry herbs in specialized shops. Dope sellers assure their customers that their products are absolu

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  • Russia Bans Blue Lotus Smoking Blends
    Light drugs are still available in free sale in Russia despite the official decree issued by Surgeon General Gennady Onischenko. One can purchase a blend of dry herbs in specialized shops. Dope sellers assure their customers that their products are absolu

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  • Ancient Psychoactive Incense and Preparations
    Psychoactive incense has been known about and used for thousands of years; Over time and after many trials mankind has discovered that a potent hallucinogenic incense could be made by combining several different plants, resins, bark and roots.Although the

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  • Ancient Psychoactive Incense and Preparations
    Psychoactive incense has been known about and used for thousands of years; Over time and after many trials mankind has discovered that a potent hallucinogenic incense could be made by combining several different plants, resins, bark and roots.Although the

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  • Empathogenic Effects of Sceletium tortuosum
    As far as being a potentiator of cannabis, there is no doubt that sceletium has this effect. Much more was gotten from much less when sceletium was added. Overall, it is my opinion that the pleasant effects of this substance, when used in moderation far o

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  • History of Sceletium tortuosum (Kanna)
    Other reports confirm that kougoed induces feelings of euphoria and deep meditative tranquility. Subjects report that the relaxation induced by kougoed enables one to focus on inner thoughts and feelings, and enables one to intensely concentrate on the be

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  • The God Chemical: Brain Chemistry And Mysticism
    Barbara Bradley Hagerty discusses the latest in brain research and the use of entheogens to induce spiritual states of mind in the laboratory. Topics covered include: Peyote ceremonies, lessons learned from scientific studies of LSD's effect on the brain,

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  • Marijuana Kills Brain Cancer Cells
    The study showed, conclusively, that THC (the active alkaloid in Cannabis) caused brain cancer cells to undergo a process called autophagy. This process causes cells to feed upon themselves, thereby destroying them, and not only did researchers witness t

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  • Melissa officinalis - Lemon Balm
    Lemon Balm has long been known for its aromatic qualities and its culinary uses. The Greeks used Lemon Balm to treat insomnia, to calm nerves and alleviate anxiety. It was used as an ingredient in Mediterranean dishes, as a garnish, as an additive to flav

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  • Ethnopharmacology of Ska María Pastora
    S. divinorum is one of several vision-inducing plants employed by the Mazatec Indians, one of the native peoples living in the mountains and upland valleys of northeastern Oaxaca. Unlike other Mexican tribes, there is little information concerning their e

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  • Spiritual Effects Of Psilocybin In Sacred Mushrooms
    In a follow-up to research showing that psilocybin, a substance contained in "sacred mushrooms," produces substantial spiritual effects, a Johns Hopkins team reports that those effects appear to last more than a year. Writing in the Journal of Psychopharm

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  • Oldest Christian Bible - Let Translations Begin!
    The early work known as the Codex Sinaiticus has been housed in four separate locations across the world for more than 150 years. Starting Monday, it became available for perusal on the Web. Scot McKendrick, head of Western manuscripts at the British Libr

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  • Salvia on Schedule: Detriment to Research
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The San Pedro Cactus, or Trichocereus pachanoi, was in use at the very beginning of Andean civilization when it was highly prized as the “materia prima” (raw material) of the shamans of that era. In the central Andes district of Peru, as well as in the surrounding desert regions, the cactus has been an important ritual plant for thousands of years. The oldest archeological proof of its ritual use was found in the layers of the formative period of the Chavin culture, when the San Pedro cactus was used both as a shamanic medicine and as a sacral inebriant. The cactus has been cultivated on the Peruvian coast since the Early Intermediate Period, 200 B.C.E. to 600 C.E.  Its history dates back to at least 1300 B.C.E., and ceramics and textiles suggest it was well known during the Chavín, Chimú, Nasca, Salinar, and Moche periods. Its present day use by curanderos in healing ceremonies in Peru, Bolivia, and Ecuador has become altered by the integration of Catholic themes with long standing indigenous beliefs.

There is very little documentation of Indian use of the San Pedro cactus dating to  the colonial period. The Inquisition did not persecute Indian use of the cactus (although it reportedly did know of its existence). Speculation has it that the name San Pedro, the Spanish variation on the name of the Catholic saint, Saint Peter, was in part bestowed on this cactus as an attempt to save it from the pharmacologic Inquisition. San Pedro is the patron saint of rain, so one can infer a direct link to the origin of its name in association with various sacramental rain cults and pagan rain gods. In addition, Saint Peter is the keeper of the keys to heaven.

There are numerous pre-Columbian artifacts from Nazca and from the Moche-Chimu period that depict columnar cacti which look exactly like Trichocereus pachanoi. An engraved image found on an ancient stele showing the oracle god of Chavin holding this exact cactus in his hand is particularly telling.  The cactus while in full bloom was found cryptically depicted on two thousand year old shamanic textiles of the Chavin culture, albeit in its idealized form, with only four ribs. It is still believed by Peruvian shamans to this day that the four ribbed San Pedro cactus is the most potent, however no actual, modern-day specimens have ever been documented in nature.

Many Mohican stirrup vessels are embellished with column shaped cacti representations, either in three dimensional relief carvings or with drawings; both types of examples are clearly indicative of shamanic associations. An ancient ceramic vessel displays an image of the magical cactus growing out of a deer – an early example of the connection made between a corvine and a plant containing mescaline. A similar connection between deer and the sacred San Pedro cactus is made in the Huichol peyote cult. A Mohican vessel with an image of an erotic scene shows a woman on her back having intercourse in the missionary position with a man who is holding a San Pedro cactus in one hand.

BOTANY OF TRICHOCEREUS:

Trichocereus bridgesii, T. macrogonus, T. pachanoi, and T. peruvianus are all closely related, some even believing they are variations of a single species. Some might even include a number of other Trichocereus in this "sliding scale." Flower and fruit similarities suggest to some that T. pachanoi and T. peruvianus are mere variations of a single species, but there is still disagreement on the subject. It has even been suggested that T. pachanoi is a cultivar of either T. bridgesii or T. peruvianus, but it continues to be the general belief that all are their own independent species even though apparent intermediary plants exist. It seems likely that such intermediary plants are the result of the importation of T. pachanoi into other areas due to its long standing enthnopharmacological value. T. pachanoi is most likely a selectively propagated species and not a selected strain of T. bridgesii or T. peruvianus.

Today, Trichocereus pachanoi is found abundantly in California, planted primarily for its enthogenic properties, although it’s a popular ornamental cactus as well. It thrives in the Californian climate and grows rapidly when watered daily. It is not a desert inhabitant; the San Pedro cactus is indigenous to the warm, humid, rain-rich areas of the Andes where it gets plenty of water. Simultaneously, it can survive months without water. Pieces cut from the cactus can survive for months, even years, and often develop lateral shoots, all without food or water.

T. pachanoi is by far one of the best grafting stocks and is often the base stock seen in photographs within numerous publications. Rib number is quite variable, usually ranging from 5 to 8. Occasionally the sacred 4 ribbed "Cactus of the Four Winds" can be observed, but 4 ribbed growth is an anomaly as the addition and subtraction of ribs during growth is quite common. The standard diameter of the species is 4," and though 8" specimens have been observed this is probably only in regard to old base material supporting large, multi-branching, plants. T. pachanoi is considered largely self-sterile and therefore it appears necessary to use different genetic stock for seed production. Much of the stock available in the US market is of a single clone introduced by Curt Backeberg, but T. pachanoi "North Peru" and "Ecuador" have been introduced into the United States market, and it will be interesting to see their variation from the Backeberg clone. Presently these two variations appear to be much more similar to T. peruvianus.

T. pachanoi can form crested plants with an elongated "fan-like" apex or monstrose specimens that have irregular growth due to the fasciation or fusing of tissue. There also appears to be a "minima/prolifera" form of T. pachanoi that has smaller growth while tillering profusely. It is my personal belief that all of these irregular forms might be more properly classified as "short spined" T. peruvianus, a plant often confused with T.pachanoi, but which may be an undescribed species. As with most cacti, variegated T.pachanoi seem to be quite rare. Recently a number of interesting T. pachanoi hybrids have been developed, particularly by Sacred Succulents.

The use of T. pachanoi as a replacement sacrament, or in grafting, by members of the Native American Church (NAC) could help preserve the natural populations of L.williamsii in the United States, but such propagation techniques are not presently accepted by the NAC.

San Pedro typically contains the following alkaloids:

Mescaline (over 25 mg per 100 grams of fresh plant)
3,4-Dimethoxyphenethylamine
3-Hydroxy-4,5-dimethoxyphenethylamine
3-Methoxytyramine
4-Hydroxy-3,5-dimethoxyphenethylamine
Anhalonidine
Hordenine
Tyramine

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RITUALISTIC USES:

The San Pedro cactus played significant ritualistic roles in oracles, sexual magic ceremonies and shamanism during pre-Hispanic times. Although no specific pre-Columbian rituals have been documented, ceremonial use of the San Pedro cactus appears to date back to very ancient times. Early earth drawings on the Nazca plain may represent consecrated cartography that Moche shamans used for their transcendent journeys into other worlds. 

The sacred cactus concoction taken by the shaman was done so largely in order to heighten their senses and enable them to recognize an illness in a patient during the ritual. The drink was sometimes given to the patient, and less frequently to others who were present. Prior to partaking the elixir, laymen would need to prime themselves by “drinking” a decoction of alcohol with tobacco extract through their nasal cavity via a snail shell or other seashell. The snail is known to be a symbol of the San Pedro cactus. This ritual would facilitate the laymen’s purification and protect them from harmful powers as they embarked on their crossing.

Modern day Peruvian shaman still ingest the sacred cactus drink during their nocturnal mesa rituals; they also may impart the sacrament onto the others who are present at these ceremonies. The “mesa,” which in Spanish simply means table, is an altar which holds numerous, significant objects such as ceramics, images of saints, shells, sticks, etc. The mesa’s structure dates back to pre-Hispanic times and lays out a visionary diagram of where the shaman will need to journey.

When taken in substantial doses, shamans use the San Pedro cactus primarily for psychedelic rituals. However, use of the San Pedro cactus elixir among Peruvian folk healers today is no longer truly shamanic. Preparations of the cactus flesh are often used as aphrodisiacs and tonics by these Peruvian medicine folk, and the drink itself has taken on a more symbolic importance to them than that of pure shamanism. At modern day mesa ceremonies, the dosage used is not large enough to elicit psychoactive effects. However, no matter its potency, the drink is said to inherently heighten visionary and diagnostic perception so that one becomes aware of the mesa objects as they begin to animate; most importantly, it allows the soul of patient to flourish.

T. pachanoi is reputedly made into the hallucinogenic beverage "cimora" in Huancabamba, Peru, and is used by curanderos for divination, the diagnosis of disease, and to "make oneself owner of another's identity." Cimora may include the cactus Neoraimondia macrostibas,Iresine spp., Brugmansia spp., Datura spp., Pedilanthus tithymaloides, and Isotoma longiflora. Though the San Pedro ceremony usually contains other plants, cimora should not immediately be assumed to contain T. pachanoi. The most recognized additives to San Pedro and/or cimora include the tropane containing Brugmansia and Datura species, but these appear to be used only for especially difficult cases needing further divination, and are usually taken only by the curandero.

An additional aspect of the ceremonies of Huancabamba is the use of "hornamo," a purgative herb. Hornamo is said to purify the participants, possibly through vomiting. Though most affiliated with Valeriana species, there exists a lengthy list of plants with some form of hornamo used in their vernacular titles. All such herbs are reputedly prepared separate from T. pachanoi, but this may not always be the case.

Nicotiana species are also commonly included within the San Pedro ceremonies, often as a liquid extract that is nasally ingested prior to the drinking of the San Pedro tea. There has been some suggestion that San Pedro is also used through nasal ingestion, but this route of administration may have its source in the Arts & Entertainment Television broadcast of the program, Ancient Mysteries: Ancient Altered States. During this program the ingestion of San Pedro was discussed alongside video of participants nasally ingesting a liquid. It appears the narration mistakenly represented this liquid as San Pedro while failing to discuss the standard oral ingestion of T. pachanoi and the well known nasal use of Nicotiana. If San Pedro is used at all by this method, then most likely it is only a ritualistic act. The volume of mescaline in such a tea would not be concentrated enough so as to prevent the participant from having to nasally ingest a truly prohibitive amount. But of course if one considers the San Pedro ceremony as a purely ritualistic act, as often appears to be the case, then the nasal ingestion of a light concentration of San Pedro tea would not be out of the question.

Generally, westerners who have participated in the San Pedro ceremonies of Huancabamba, Peru, rarely feel the full psychoactive potential of the mescaline present in T. pachanoi. This is often a simple matter of dosage, something the curandero holds sway over as much as the Roman Catholic priest does of the Eucharist (Wade 1983). And like the taking of the Eucharist, the ingestion of San Pedro has largely become a ceremonial act in which the ritual performed plays a larger part in the healing than does direct access to the spiritual otherworld.

Due to such ceremonial and ritualistic use of the species, it may be possible that Armatocereus laetus and Espostoa lanata, other cacti reputedly used by similar means as T. pachanoi in Huancabamba, Peru, may not have psychopharmacological effect.

SAN PEDRO PREPARATION:

The San Pedro drink is made using fresh cactus stalks or pieces. You boil the chopped cactus for a few hours in plenty of water. Often other plants are added to this mixture, such as misha, hornamo or condorillo. The decoction is then poured off and boiled again for several hours until only about half of the original volume remains. Some folk healers use the recipe of boiling four thin stalks in approximately five gallons of water for seven hours. Usually one piece of cactus, roughly two to three inches thick and ten inches long is a sufficient dose for each person who will be imbibing the drink. It is sliced into sections and then boiled. Adding lime or lemon juice to the brew helps to dissolve the mescaline, assisting it in leeching into the liquid.

To harvest, the stalks are cut off some four inches or so above the ground. The remaining stumps will sprout shoots again in no time. The stalks should be cut into manageable pieces, about ten to fifteen inches in length, and then the ribs are cut away. The outer rind is sliced from the flesh where the green color of the flesh stops. The fresh skin is laid in the sun to dry for a few hours, then as it starts to curl up, it should be flipped so that the fresh skin is exposed. The drying process needs to be repeated, which in total can take from two to six days.

After thoroughly drying the cactus skins, one grinds them to a fine powder by using a mortar and pestle, a grinding stone, a coffee grinder or a professional device from a pharmacy made for pulverizing the raw material. The important thing to remember is that the finer the powder, the more effective the absorption of the mescaline. Since the cactus powder is unpalatably bitter, many people put the powder into gelatin capsules that hold one gram each. This practice makes it easier to digest and enables the dosage to be as exact as possible.

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